Design and Simulation of the Spiral Micromixer with Chaotic Advection

Document Type : Regular Article


Department of Mechanical Engineering, Delhi Technological University, Delhi, 110042, India



In recent years, the microfluidics technique has screwed up rising attention and be in progress a fascinating topic. Species mixing is a compelling part of any microfluidic system that abides by the major challenge. In this research, a relative explication of mixing quality of microchannels of two cross-sections square and circular in spiral form is presented by numerical simulation. To perform the visitation, geometric parameters like axial length of microchannels and hydraulic diameter are taken equal for both cases. Computational Fluid Dynamics codes unriddle the Continuity equation, Navier-Stokes equation, and Convection-Diffusion equation. Explication of fluid flow and mixing have been gone through with an extensive limit of Reynolds numbers 1 to 125. The results explicate that the circular section spiral microchannel affords a higher mixing quality admixed to the square section spiral microchannel. Furthermore, in the circumstance of circular section spiral micromixer, mixing index esteem has attained 92% at Re =125.  For both section micromixer, the esteem of mixing index enhancement be contingent on Reynolds numbers. For both cases, pressure downfall has been computed for microchannels of similar lengths. The esteem of pressure downfall in square section spiral mixer is excess than circular section spiral mixer. The simulation outcomes exhibited that the circular section spiral micromixer is an effective design for microfluidic devices like Lab on a chip (LOC).


Azmi, W. H., K. A. Hamid, A. I. Ramadhan and A. I. M. Shaiful (2021). Thermal hydraulic performance for hybrid composition ratio of Tio2- Sio2 nanofluids in a tube with wire coil inserts. Case Studies in Thermal Engineering 25, 100899.##
Balasubramaniam, L., R. Arayanarakool, S. D. Marshall, B. Li, P. S. Lee and P. C. Y. Chen (2017). Impact of cross-sectional geometry on mixing performance of spiral microfluidic channels characterized by swirling strength of Dean-vortices. Journal of Micromechanics and Microengineering 27, 095016.##
Cao, X., K. Yang, T. Li, N. Xiong, W. Yang and J. Bian (2021). Numerical simulation of hydrate particle behaviors in gas-liquid flow for horizontal and inclined pipeline. Case Studies in Thermal Engineering 27, 101294.##
Chen, Y. and X. Chen (2019). An improved design for passive micromixer based on topology optimization method. Chemical Physics Letters 734, 136706.##
Dong, S., P. F. Geng, D. Dong and C. X. Li (2020). Mixing enhancement of electroosmotic flow in microchannels under DC and AC electric field. Journal of Applied Fluid Mechanics 13(1), 79-88.##
Farahinia, A., J. Jamaati, H. Niazmand and W. Zhang (2021). The effect of heterogeneous surface charges on mixing in a combined electroosmotic/pressure-driven micromixer, Journal of the Brazillian Society of Mechanical Sciences and Engineering 43, 497.##
Farahinia, A., W. J. Zhang and I. Badea (2020a). Circulating Tumor Cell Separation of Blood Cells and Sorting in Novel Microfluidic Approaches: a review. Journal of Science: Advanced Materials and Devices doi: 10.20944/preprints202010.0622.v1.##
Farahinia, A. and W. J. Zhang (2020b). Numerical analysis of a microfluidic mixer and the effects of different cross-sections and various input angles on its mixing performance. Journal of the Brazillian Society of Mechanical Sciences and Engineering 42, 190.##
Farahinia, A. and W. J. Zhang (2019). Numerical investigation into the mixing performance of micro T-mixers with different patterns of obstacles. Journal of the Brazillian Society of Mechanical Sciences and Engineering 41, 491.##
Ghazimirsaeed, E., M. Madadelahi, M. Dizani and A. Shamloo (2021). Secondary flows, mixing, and chemical reaction analysis of droplet based flow inside serpentine microchannels with different cross-sections. Langmuir 37(17), 5118-5130.##
Hasanah, L., D. F. Nurvadila, R. E. Pawinanto, B. Mulyanti, C. Wulandari, A. Aminudin and J. Yunas (2022). A passive micromixer with Koch Snowflakes Fractal obstacle in microchannel. Journal of Applied Fluid Mechanics 15(5), 1333-1344.##
Hossain, S., M. A. Ansari and K. Y. Kim (2009). Evaluation of the mixing performance of three passive micromixers. Chemical Engineering Journal 150, 492-501.##
Jiang, Y., B. Zhang, Y. Tian, Y. Zhang and Y. Chen (2022). Analysis of different shapes of cross-sections and obstacles in variable-radius spiral micromixers on mixing efficiency. Chemical Engineering and Processing Process Intensification 171, 108756.##
Kockmann, N., M. Engler, C. Fo’’ll and P. Woias (2003). Liquid mixing in static micromixers with various cross-sections. In Ist International Conference on Microchannels and Minichannels 911-918.##
Li, Y., D. Zhang, X. Feng, Y. Xu and B. F. Liu (2012). A microsecond microfluidic mixer for characterizing fast biochemical reactions. Talanta 88, 175-180.##
Liu, G., M. Wang, P. Li, X. Sun, L. Dong and P. Li (2022). A micromixer driven by two valveless piezoelectric pumps with multistage mixing characteristics. Sensors and Actuators: A. Physical 333, 113225.##
Liu, G., X. Ma, C. Wang, X. Sun and C. Tang (2018). Piezoelectric driven self-circulation micromixer with high frequency vibration. Journal of Micromechanics and Microengineering 28, 085010.##
Mondal, B., S. Pati and P. K. Patowari (2021). Serpentine square wave microchannel fabrication with WEDM and soft lithography. Materials Today: Proceedings 46, 8513-8518.##
Nezhad, J. R. and S. A. Mirbozorgi (2018). An immersed boundary-lattice Boltzmann method to simulate chaotic micromixers with baffles. Computers and Fluids 167, 206-214.##
Nouri, D., A. Z. Hesri and M. P. Fard (2017). Rapid mixing in micromixers using magnetic field. Sensors and Actuators A 255, 79-86.##
Pang,Y., Q. Zhou, X. Wang, Y. Lei, Y. Ren, M. Li, J. Wang and Z. Liu (2020). Droplets generation under different flow rates in T-junction microchannel with a neck. AIChE Journal 66(10), 16290.##
Prakash, R., M. Zunaid and Samsher (2021). Simulation analysis of mixing quality in T-junction micromixer with bend mixing channel. Materials Today: Proceedings 47, 3833-3838.##
Quiyoom, A., V. V. Buwa and S. K. Ajmani (2017). Role of free surface on gas-induced liquid mixing in a shallow vessel. AIChE Journal 63(8), 3582-3598.##
Redapangu, P. R., T. G. Kidan and K. Berhane (2021). Mixing and interpenetration in a three dimensional Buoyancy-Driven flow of two immiscible liquids: A GPU based LBM Approach. Journal of Applied Fluid Mechanics 14(2), 601-613.##
Rouhi, O., S. R. Bazaz, H. Niazmand, F. Mirakhorli, S. M. hafi, H. A. Amiri, M. Miansari and M. E. Warkiani (2021). Numerical and experimental study of cross-sectional effects on the mixing performance of the spiral microfluidics. Micromachines 12, 1470.##
Ruijin, W., L. Beiqi, S. Dongdong and Z. Zefei (2017). Investigation on the splitting-merging passive micromixer based on Baker’s transformation. Sensors and Actuator B 249, 395-404.##
Saleel, C. A., A. Algahtani, I. A. Badruddin, T. M. Yunus Khan, S. Kamangar and M. A. H. Abdelmohimen (2020). Pressure-Driven Electro-Osmotic Flow and Mass Transport in Constricted Mixing Micro-channels. Journal of Applied Fluid Mechanics 13(2), 429-441.##
Santana, H. S., J. L. Silva Jr and O. P. Taranto (2019). Optimization of micromixer with triangular baffles for chemical process in millidevices. Sensors and Actuators B: Chemical 281, 191-203.##
Seo, H. S. and Y. J. Kim (2012). A study on the mixing characteristics in a hybrid type microchannel with various obstacle configurations. Materials Research Bulletin 47, 2948-2951.##
Shimizu, H. and Y. Uetsuji (2022). Fluid-structure and electric coupled analysis of a valveless microfluidic system using metal-capped piezoelectric actuator. Sensors and Actuators A: Physical 333, 113232.##
Shinde, A. B., A. V. Patil and V. B. Patil (2021). Enhance the mixing performance of water and ethanol at micro level using geometrical modifications. Materials Today: Proceedings 46, 460-470.##
Tokas, S., M. Zunaid and M. A. Ansari (2021). Non-Newtonian fluid mixing in a Three Dimensional spiral passive micromixer. Materials Today: Proceedings 47, 3947-3952.##
Tony, A., A. Rasouli, A. Farahinia, G. Wells, H. Zhang, S. Achenbach, S. M. Yang, W. Sun and W. Zhang (2021). Toward a Soft Microfluidic System: Concept and Preliminary Developments. In 27th International Conference on Mechatronics and Machine Vision in Practice, 755-759.##
Umadevi, C., M. Dhange, B. Haritha and T. Sudha (2021). Flow of blood mixed with copper nanoparticles in an inclined overlapping stenosed artery with magnetic field. Case Studies in Thermal Engineering 25, 100947.##
Vatankhah, P. and A. Shamloo (2018). Parametric study on mixing process in an in-plane spiral micromixer utilizing chaotic advection. Analytica Chimica Acta 1022, 96-105.##
Wu, B., C. Li, M. Zhand and P. Luo (2021). Liquid mixing intensification by adding swirling flow in the transverse jet mixer. AIChE Journal 67(8), 17276.##
Xia, G. D., Y. F. Li, J. Wang and Y. L. Zhai (2016). Numerical and experimental analyses of planar micromixer with gaps and baffles based on field synergy principle. International Communications in Heat and Mass Transfer 71, 188-196.##
Xu, Z., C. Li, D. Vadillo, X. Ruan and X. Fu (2011). Numerical simulation on fluid mixing by effects of geometry in staggered oriented ridges micromixers. Sensors and Actuator B 153, 284-292.##
Yang, S. M., S. Lv, W. Zhang and Y. Cui (2022). Microfluidic Point-of-Care (POC) Devices in Early Diagnosis: A Review of Opportunities and Challenges. Sensors 22, 1620.##
Zhang, S., X. Chen, Z. Wu and Y. Zheng (2019). Numerical study on stagger Koch fractal baffles micromixer. International Journal of Heat and Mass Transfer 133, 1065-1073.##